Understanding melanoma: The signs, symptoms and risk factors
April 15, 2021

What is melanoma?
Melanoma is the most serious form of skin cancer. Characterized by the uncontrolled growth of pigment-producing cells, melanoma accounts for approximately 2% of new cancer cases worldwide.
Melanomas can occur anywhere on the skin, including areas without sun exposure, but they are more likely to start in certain locations.

The average age of diagnosis is 65, but melanoma is not uncommon among people younger than 30. In fact, it’s one of the most common cancers in young adults — especially young women.
Rates have been rising for 30 years

people diagnosed with melanoma
deaths
Signs and symptoms
A new spot on the skin — one that changes in size, shape or color, or one that looks different — is an important warning sign of melanoma and should be checked by a doctor. The ABCDE rule outlines the characteristics of moles that may be melanomas and is helpful guidance for monitoring skin changes:

A is for Asymmetry
One half of a mole or birthmark does not match the other.

B is for Border
The edges are irregular, ragged, notched or blurred.

C is for Color
The color is not the same all over and may include different shades of brown or black, or sometimes with patches of pink, red, white, or blue.

D is for Diameter
The spot is more than 6 millimeters across (about 1/4 inch – the size of a pencil eraser), although melanomas can sometimes be smaller than this.
E is for Evolving
The mole is changing in size, shape, or color.

Any of these warning signs should be discussed with a doctor, especially if you feel you are at risk for melanoma.
Risk factors
- Ultraviolet (UV) light exposure
- Moles
- Fair skin, freckles and light hair
- Family history
- Personal history of having melanoma or other skin cancers
- Having a weakened immune system
- Being older
- Being male
- Xeroderma pigmentosum (a rare skin condition that affects the skin’s ability to repair DNA damage)
Ways to help lower risk
Melanoma can’t be entirely prevented, but there are ways to help lower risk. The number one way to lower risk is to protect against UV rays, which damage the DNA of skin cells and impact the genes that control skin cell growth. The top source of UV rays is the sun. That’s why it’s important to practice sun safety every time you go outside, even on cloudy days when UV rays can still shine through. Here are a few ways to protect yourself:

Seek shade
UV exposure is greatest between the hours of 10 a.m. and 4 p.m. If you need to be outside during these hours, seek shade – under a tree, an umbrella or an awning.

Wear a hat
Try to find a hat with a wide brim – at least 2 or 3 inches wide – to protect your face, top of the head, ears and neck.

Cover up
Choose clothing with a tight knit or weave, and avoid shirts that you can see through. Remember, if light is getting through, then UV rays are too.

Use sunscreen
For extended outdoor activity, use a water-resistant, broad spectrum sunscreen with an SPF of 30 or higher.

Wear sunglasses
Protect your eyes and the sensitive skin around them. Pick a pair that will block as close to 100 percent of both UVA and UVB rays as possible.